Iridium (III)??Catalyzed Approach for the Synthesis of Fused Arenes: Access to Isoindolines, Indanes, and Dihydroisobenzofurans

…, M Ez??Zoubir, S Bompard, MR Vitale, JA Brown…

Index: Auvinet, Anne-Laure; Ez-Zoubir, Mehdi; Bompard, Savinien; Vitale, Maxime R.; Brown, Jack A.; Michelet, Veronique; Ratovelomanana-Vidal, Virginie ChemCatChem, 2013 , vol. 5, # 8 p. 2389 - 2394

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Citation Number: 2

Abstract

Abstract A facile and efficient method for the synthesis of isoindoline, indane, and dihydroisobenzofuran derivatives has been developed through the application of a halogen- bridged iridium (III) complex to the [2+ 2+ 2] cycloaddition of α, ω-diynes with alkynes. The cycloaddition tolerates a broad range of substitution groups, such as alcohol, alkyl, ether, and halogen, and the chemistry can be extended to prepare the corresponding borylated ...