Simple and convenient conversion of acridones into 9-unsubstituted acridines via acridanes using borane tetrahydrofuran complex

…, V Weber, E Moreau, JC Teulade, O Chavignon…

Index: Desbois, Nicolas; Szollosi, Anna; Maisonial, Aurelie; Weber, Valerie; Moreau, Emmanuel; Teulade, Jean-Claude; Chavignon, Olivier; Blache, Yves; Chezal, Jean Michel Tetrahedron Letters, 2009 , vol. 50, # 49 p. 6894 - 6896

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Citation Number: 6

Abstract

A new method for the synthesis of 9-unsubstituted acridines from acridones using mild conditions is described. Various acridines bearing reduction-sensitive group (s) have been synthesized from the corresponding acridones using a two-step procedure that involved a commercially available borane complex reduction followed by an acridane oxidation.