Abstract Methyl trans-chrysanthemate has been prepared in few steps from isopropylidenediphenylsulfurane and methyl (E)-3-(3, 3-dimethyloxiran-2-yl) prop-2-enoate. The latter was obtained from methyl 4-oxobutenoate or 3-methylbut-2-en-1-ol. The Sharpless catalytic epoxidation reaction allows an asymmetric version of this transformation.
![[(2R)-3,3-dimethyloxiran-2-yl]methyl 4-nitrobenzoate Structure](https://image.chemsrc.com/caspic/149/141700-91-6.png)
