Dehydrocyclization of 4-Amino-5-arylamidopyrimidines to Purines with Polyphosphoric Acid1a, b

SCJ Fu, E Chinoporos, H Terzian

Index: Fu,S.-C.Y. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 1916 - 1920

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Citation Number: 17

Abstract

Several 8-arylpurines have been synthesized by cyclization of 4-amino-5- arylamidopyrimidines with phosphorus oxychloride2J or phosphorus oxybromide, 2 by dry heating of the pyrimidines2e4 and by other appro ache^.^,^ However, no single method was found effective and applicable to the synthesis of all% arylpurines.(1)(a) Presented in part before the Organic Chemistry Division, 147th National Meeting of the American Chemical ...