A comparison of methods for N-oxidation of some 3-substituted pyridines

…, G Wishart, SR Mitchell, SM Nicoll, G Jones

Index: Bremner, David H.; Sturrock, Keith R.; Wishart, Grant; Mitchell, Stewart R.; Nicoll, Stuart M.; Jones, Gareth Synthetic Communications, 1997 , vol. 27, # 9 p. 1535 - 1542

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Citation Number: 16

Abstract

Abstract: The results from the N-oxidation of four 3-substituted pyridines using five different reagents are reported. The best yields are obtained with m- chloroperoxybenzoic acid. ... As part of a synthetic programme investigating the synthesis and reactions of ... (method F). Although, the oxidation of pyridines to their corresponding pyridine ... N-oxides is not new, this comparison will prove useful to others when cost and ... The yields of products (2a-d) obtained by the oxidation ...