Synthesis and Evaluation of Novel Phenylethanolamine Derivatives containing Acetanilides as Potent and Selective. BETA. 3-Adrenergic Receptor Agonists

T Maruyama, K Onda, M Hayakawa, T Suzuki…

Index: Chemical and Pharmaceutical Bulletin, , vol. 58, # 4 p. 533 - 545

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Citation Number: 9

Abstract

... 2010 Pharmaceutical Society of ... Chemistry The synthesis of 2-pyridylacetanilides 5a— c, 8a,b, and 9a—d are shown in Chart 1. Treatment of 4-(2 ... 1H-NMR spectra were recorded on a JEOL EX90, EX400, or GX500 spectrometer, and the chemical shifts are ex- pressed in d (ppm ...