Biosynthesis of 2??Alkyl??4 (1H)??Quinolones in Pseudomonas aeruginosa: Potential for Therapeutic Interference with Pathogenicity

D Pistorius, A Ullrich, S Lucas, RW Hartmann…

Index: ChemBioChem, , vol. 12, # 6 p. 850 - 853

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Citation Number: 33

Abstract

... ChemBioChem, 12: 850–853. ... Volume: Issue: Page ... precursor 2-heptyl-4(1H)-quinolone (HHQ) are used (see Scheme 1).4 The pqs system is involved in the regulation of P. aeruginosa virulence such as pyocyanin biosynthesis,5 biofilm formation and maturation,6 the production ...