Synthesis of captopril starting from an optically active. BETA.-hydroxy acid.

島崎正美， 長谷川淳三， 菅和憲， 野村憲二…

Index: Chemical and Pharmaceutical Bulletin, , vol. 30, # 9 p. 3139 - 3146

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Citation Number: 57

Abstract

... Nevertheless if such direct substitution could be conducted with retention of the stereo— chemistry of the ... 1: 1, by VOL). ... values of 0.31 (1), 0.19 (5) and 0.14 (6). They were all isolated by silica gel column chromatography (Wakogel C200, supplied by wako Pure Chemical Incl, Co ...