Bioorganic & medicinal chemistry

Pyrrolidine carbamate nucleic acids: Synthesis and DNA binding studies

VA Kumar

Index: Meena; Kumar, Vaijayanti A. Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 16 p. 3393 - 3399

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Citation Number: 4

Abstract

An efficient solid phase synthesis of pyrrolidine carbamate nucleic acids is reported. The protected (2S, 4S)-4-aminopyrrolidine-2-methanol with nucleobases thymine and cytosine attached to the ring nitrogen through an acetyl linker can be activated as nitrophenyl