Aristolochene biosynthesis and enzymatic cyclization of farnesyl pyrophosphate

…, PHM Harrison, H Noguchi, BJ Rawlings

Index: Cane; Prabhakaran; Salaski; Harrison; Noguchi; Rawlings Journal of the American Chemical Society, 1989 , vol. 111, # 24 p. 8914 - 8916

Full Text: HTML

Citation Number: 56

Abstract

IC Id the structure of the enzymatic cyclization product. When an analogous incubation was carried out using [12, 13-14C] FPP (2b), I2 selective oxidation (Os04 followed by NaI04) of the derived aristolochene (lb) gave the methyl ketone 4 (semicarbazone, 6.61 X IO4 dpm/ ...