e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Evidence for an Intermediate in the Methylation of CB11H12− with Methyl Triflate: Comparison of Electrophilic Substitution in Cage Boranes and in Arenes
Abstract The trideuteriomethylation of BH vertices in CB 11 H 12− and its derivatives with CD 3 OTf (OTf= triflate, trifluoromethanesulfonate) yields a mixture of B [BOND] CD 3 and B [BOND] CHD 2 substitution products, thus demonstrating the intermediacy of a species with a long enough lifetime for hydrogen scrambling between the boron vertex and the methyl substituent. No such scrambling is observed if CD 3 OTf is used to methylate toluene. ...