Tetrahedron

Enantioselective total synthesis and correction of the absolute configuration of megislactone

GB Ren, Y Wu

Index: Ren, Guo-Bao; Wu, Yikang Tetrahedron, 2008 , vol. 64, # 19 p. 4408 - 4415

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Citation Number: 6

Abstract

The title compound, one of the constituents from Iryanthera megistophylla, has been synthesized in enantiopure forms. The stereogenic centers at C-2 and C-3 were constructed by using a chiral auxiliary induced asymmetric aldolization and the C-4 was derived from the