Abstract We report a new and facile synthetic approach to N α-Boc ureidoalanine derivatives from commercially available Boc-l-aspartic acid. Not only N′-substituted but also N′, N′- disubstituted ureidoalanine derivatives may be obtained by this method. The key aspect of this method is the employment of a 5-oxazolidinone to provide proper protection of the α- nitrogen of l-aspartic acid. This ensures successful obtainment of the corresponding ...
