Since the preparation of 5, 5-diethylbarbituric acid (Verona1 or Barbital) by Fischer and von Mering, and the subsequent discovery of its hypnotic properties, a large amount of research has been carried out with a view to securing hypnotics superior to this substance. In general these attempts have centered on substitution in Position 5, in which the effect of a very large number of organic radicals has been investigated. Among these, ether groups2 of the ...