Abstract In search of novel nonsteroidal mimics of steroidal inhibitors of 5α reductase, 4-(2- phenylethyl) cyclohex-1-ene carboxylic acids 1—5 were synthesized with different substituents in para position of the phenyl ring (1: N, N-diisopropylcarbamoyl, 2: phenyl, 3: phenoxy, 4: benzoyl, and 5: benzyl). The principal synthetic approach for the desired compounds consisted of a Wittig olefination between 1, 4-dioxaspiro [4.5]-decane-8- ...
