Stereoselective intramolecular bis-silylation of alkenes promoted by a palladium-isocyanide catalyst leading to polyol synthesis

…, M Suginome, K Fujimoto, H Nakamura…

Index: Murakami, Masahiro; Suginome, Michinori; Fujimoto, Kenzo; Nakamura, Hiroshi; Andersson, Pher G.; Ito, Yoshihiko Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6487 - 6498

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Citation Number: 120

Abstract

Abstract: Details of a study on the intramolecular bis-silylation of terminal alkenes promoted by a palladium-tert-alkyl isocyanide catalyst are described. With a disilanyl ether derived from a homoallylic alcohol, intramolecular regioselective addition of the Si-Si linkage to the C= C bond took place to furnish an exo-ring closure product, ie, 1, 2-oxasilolane. The bis- silylation of alkenes having substituents a to the C= C bond gave trans-3, 4-disubstituted ...