Polycondensed nitrogen heterocycles. Part 19. Pyrrolo [1, 2??f] phenanthridines by pschorr??type cyclization brought about by hypophosphorous acid

G Dattolo, G Cirrincione, AM Almerico…

Index: Dattolo; Cirrincione; Almerico; et al. Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 5 p. 1371 - 1373

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Citation Number: 8

Abstract

Pyrrolophenanthridine derivative, obtained from Ama- ryllidaceae, have shown anticancer activity [2-51, but vir- tually nothing is known about the pharmacological pro- perties of pyrrolo[ 1,24phenanthridines, since the reports on this ring system are limited only to the synthesis. Routes leading to the title compounds reported so far have involved the annelation of a pyrrole ring to the phenanth- ridine nucleus [6]. In connection with our studies on poly- condensed ...