The Oxidation of 2, 4, 6-Trimethylphenol with Molecular Oxygen Catalyzed by a Copper (II)-Oxime or Copper (II)-Amine System.

M Shimizu, Y Watanabe, H Orita, T Hayakawa…

Index: Shimizu, Masao; Watanabe, Yoshihito; Orita, Hideo; Hayakawa, Takashi; Takehira, Katsuomi Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 1 p. 251 - 257

Full Text: HTML

Citation Number: 30

Abstract

2, 4, 6-Trimethylphenol (1a) was selectively oxidized to 3, 5-dimethyl-4- hydroxybenzaldehyde (2a) by molecular oxygen in the presence of a copper (II) chloride- oxime or copper (II) chloride-amine catalyst in alcohol at ambient temperature. When an acid was present in the catalyst system, the formation of both 2, 6-dimethyl-p-benzoquinone (3) and a formaldehyde dialkyl acetal was accelerated. It is likely that 2a is produced by way ...