DABCO-POCl3, A mild dehydrating agent for the preparation of nitriles from aldoximes

…, K Bakhtiari, RH Shoar, HA Oskooie

Index: Heravi, Majid M.; Bakhtiari, Khadijeh; Shoar, Rahim Hekmat; Oskooie, Hossein A. Journal of Chemical Research, 2005 , # 9 p. 590 - 591

Full Text: HTML

Citation Number: 4

Abstract

Nitriles are versatile functional groups. They are classified as carboxylic acid derivatives because they can be converted to carboxylic acids on hydrolysis under acidic and basic conditions. They can also be converted to amides via nucleophilic addition of water and ketones via hydrolysis of the imine formed by the nucleophilic addition of a Grignard reagent. 1