THIONO COMPOUNDS. 8. MUTAGENIC ACTIVITY OF REPRESENTATIVE AMIDES OF THIOPHOSPHORIC ACID

WM Mitchell, AP Breau, J Swinson…

Index: Mitchell, William M.; Breau, Alan P.; Swinson, Joel; Field, Lamar Phosphorus and Sulfur and the Related Elements, 1988 , vol. 35, p. 151 - 158

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Abstract

Abstract Amides of thiophosphoric acid were studied, in order to initiate correlations of mutagenicity with structure, by use of a modified Ames assay. Representative thiophosphoramides of the structure (XArNH) 3PS were not mutagenic, irrespective of whether X was a reference hydrogen atom, an electron-withdrawing, or an electron-donating group. One phosphoramidothioate of the structure (2, 4-X2ArNH) P (S)(OCH2CH3) 2 ...