The conversion of 2-phenyl-4-chloromethylthiazole to 2-phenyl-4-hydroxymethyl-5-chlorothiazole

EH Huntress, K Pfister 3rd

Index: Huntress; Pfister Journal of the American Chemical Society, 1943 , vol. 65, p. 1667,1669

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Citation Number: 10

Abstract

Summary A new benzylidene-D-arabitol has been obtained by the debenzoylation of the 1, 5-dibenzoylbenzylidene-D-arabitol that is obtained by condensing 1, 5-dibenzoyl-~-arabitol with benzaldehyde under the catalytic action of fused zinc chloride. The new acetal has been shown to be 2, 3-benzylidene-~-arabitol since it is oxidized by sodium periodate to a sirupy product, presumably 2, 3-benzylidene-~-threose, which gives a quantitative yield of ...