Design, synthesis, cytoselective toxicity, structure–activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells

H Zhou, S Wu, S Zhai, A Liu, Y Sun, R Li…

Index: El'tsov; Mokrushin; Bel'skaya; Kozlova Russian Chemical Bulletin, 2003 , vol. 52, # 2 p. 461 - 466

Full Text: HTML

Citation Number: 135

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... Collaborations in Chemistry. , ⊥ ... Using Lipinski's rule of five selection criteria, 120 compounds were eliminated. Chemical feasibility and building block validation studies eliminated another 24 compounds. ...