Abstract:'H and I3C NMR studies indicate that the predominant stereoisomer and conformer in solution for the potent natural antitumor agents deoxybouvardin (l), bouvardin (2), and the newly isolated and equally active 6-0-methylbouvardin (3) is that found in the solid state by X-ray diffraction. Unusual features in the spectra, all in the vicinity of the 14-membered ring, include an aromatic proton absorbing unusually far upfield at S 4.35, a vicinal HC-0-H ...
