Tetrahedron Letters

(7E, 13ξ, 15Z)-14, 16-dibromo-7, 13, 15-hexadecatrien-5-ynoic acid. A novel dibromo acetylenic acid from the marine sponge Xestospongia muta

FJ Schmitz, Y Gopichand

Index: Schmitz,F.J.; Gopichand,Y. Tetrahedron Letters, 1978 , p. 3637 - 3640

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Citation Number: 47

Abstract

In earlier papers1 we have described the isolation from a sea hare of two halogenated acetylenic Cl5 straight-chain ethers, one of which exhibits the interesting pharmacologic property of markedly potentiating the activity of pentobarbital in mice. 2 In our continuing search3 for bioactive compounds from marine organisms we have isolated a dibrominated straight-chain Cl6 acetylenic acid, the first compound of this type to be reported, and we ...