A series of bis (N-methylcarbamate) and bis [N-(2-propy1) carbamatel derivatives of 5- substituted 6, 7-bis (hydroxy-methyl) pyrrolo [l, 2-c] thiazoles was prepared. The compounds were tested for activity in vivo against P388 lymphocytic leukemia, and the chemical reactivities of the compounds were compared by using the model nucleophile 4-(4- nitrobenzy1) pyridine (NBP). The 5-(3, 4-dichlorophenyl)-substituted biscarbamates 6b, ...
