Tetrahedron: Asymmetry

Studies on the structure–enantioselectivity relationships in the catalytic asymmetric intramolecular cyclopropanation reaction of α-diazo-β-keto sulfones possessing a …

H Takeda, M Nakada

Index: Takeda, Hiroyuki; Nakada, Masahisa Tetrahedron Asymmetry, 2006 , vol. 17, # 20 p. 2896 - 2906

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Citation Number: 28

Abstract

This manuscript describes studies on structure–enantioselectivity relationships in the catalytic asymmetric intramolecular cyclopropanation (IMCP) reaction of α-diazo-β-keto sulfones possessing a methyl-substituted phenyl group. Enantioselectivity of the IMCP reaction of the α-diazo-β-keto sulfones was varied by the position of a methyl group on the phenyl group in the substrate, and the 2, 3-dimethylphenyl sulfone 11h provided the ...

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