Radiosyntheses and reactivities of novel [18F] 2??fluoroethyl arylsulfonates

JL Musachio, J Shah, VW Pike

Index: Musachio, John L.; Shah, Jay; Pike, Victor W. Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 10 p. 735 - 747

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Citation Number: 18

Abstract

Abstract [18 F] 2-Fluoroethyl tosylate ([18 F] FEOX, X= Ts) is widely used for labeling radiotracers for positron emission tomography (PET). Little work has been reported on syntheses of other [18 F] 2-fluoroethyl arylsulfonates ([18 F] FEOX) that bear a less electron- rich aryl group, even though these might offer enhanced reactivities. Thus, a series of novel [18 F] FEOX (X= benzenesulfonyl, brosyl, nosyl, 3, 4-dibromobenzenesulfonyl) were ...