Abstract A new series of channel-type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a β-cyclodextrin derivative 3 that constitutes the organizing core. They belong to the 'bouquet'family (B). Compounds bearing poly (oxyethylene) side chains, B math image 16 and 17, and their polymethylene analogues B math image 18 and 19, were ...