Abstract: A facile synthesis of fulgenic acid (1) via 1, 4-dehydrobromination of (bromomethyl) methylmaleic anhydride (2) using aqueous KOH, t-BuOK in THF, and NaH in benzene in 60– 85% yield is described. The newly synthesized (hydroxymethyl) methylmaleic anhydride (3) also underwent smooth 1, 4-elimination in the presence of aqueous KOH to yield 1. Key words:(bromomethyl) methylmaleic anhydride, base, 1, 4-elimination, fulgenic acid
[Buckel, Wolfgang; Pierik, Antonio J.; Plett, Sandra; Alhapel, Ashraf; Suarez, Diana; Tu, Shang-Min; Golding, Bernard T. European Journal of Inorganic Chemistry, 2006 , # 18 p. 3622 - 3626]
