6080 LLOYD H. SBIITH, JR., AND PETER YATES ... Procedure B. Ethyl truns-4-Acetyl-2,5-dimethyl -l-piper- azinecarboxylate (V).-A mixture of 18.6 g. (0.1 mole) of ethyl tr~ns-2,5-dimethyl-l-piperazinecarboxylate ~~ and 25 ml. of acetic anhydride was refluxed for 8 hours. The re- sulting solution was distilled in vucuo. After removal of acetic acid and acetic anhydride two fractions were ob- tained: (a) 7.2 g. of colorless liquid, bp 128-143" (15 mm.) (mainly ethyl truns-2,5-dimethyl-l- ...
