O-Carbamyl-L-serine, an inhibitory analog of L-glutamine

CG Skinner, TJ McCord, JM Ravel…

Index: Skinner et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 2412

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Citation Number: 22

Abstract

0-Carbamyl-L, D-and DL-serine have been prepared through interaction of L, D-and DL-N- carbobenzoxyserine benzyl ester with phosgene followed by treatment with ammonium hydroxide and hydrogenolysis. The L-derivative inhibits growth of Streptococcus lactis 8039, Lactobaczllus arnbinosus 17-5 and Escherichia coli 9723, whereas the D-isomer is not inhibitory even at high levels. The inhibition of growth of S Zactis by 0-carbamylserine is ...