Journal of medicinal chemistry

Analogs of Steroid Hormones. I. 6-(4-Oxocyclohexenyl) and 6-(p-Hydroxyphenyl) Derivatives of 2-Naphthalenone1

RE Juday, DP Page, GA Du Vall

Index: Juday,R.E. et al. Journal of Medicinal Chemistry, 1964 , vol. 7, p. 519 - 524

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Citation Number: 1

Abstract

IIa auxiliary solvents and thus failed to reduce. It was found that morpholine was a much inore effective solvent in this reaction, although reduction was still not complete when there were two rings to reduce. It Fas also noted that a niethyl ortho to the inethoxyl in the benzene ring prevented reduction of that ring. To prepareVIb and c, the dihydropyraii adduct of p- broinophenol was used instead of p-bromoanisole in inaking the lithiuni reagent to react ...