e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The Dehydrogenation of Corticosteroids with Chloranil1
EJ Agnello, GD Laubach
Index: Agnello; Laubach Journal of the American Chemical Society, 1957 , vol. 79, p. 1257 Journal of the American Chemical Society, 1960 , vol. 82, p. 4293,4297
In the course of a study of new methods for the dehydrogenation of steroid 3-ketones, it was found that the treatment of A4-3-ketosteroids with chloranil (tetrachloro-$-benzoquinone) can afford A6-dehydro or A1t6-bisdehydro derivatives depending on the reaction conditions employed. A preliminary report of this single step method of synthesizing dehydro derivatives of corticosteroids from A4-3-ketones has been published. 2 In the
