Tetrahedron letters

Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4, 4′-bipyrazole derivatives

M Bakavoli, B Feizyzadeh, M Rahimizadeh

Index: Bakavoli, Mehdi; Feizyzadeh, Babak; Rahimizadeh, Mohammad Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8965 - 8968

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Citation Number: 20

Abstract

The addition of hydrazine to functionalized furans 2a–d leads to a variety of 4, 4′- bipyrazoles 4a–c depending on the structure of the starting materials. In one example, compound 2c was first converted to an intermediate, furo [3, 4-d] pyridazine 3c which was then transformed into 4, 4′-bipyrazole 4c on reacting with hydrazine.