Synthesis of (S)-3-(N-Methylamino)-1-(2-thienyl) propan-1-ol: Revisiting Eli Lilly's Resolution-Racemization-Recycle Synthesis of duloxetine for its robust processes

Y Fujima, M Ikunaka, T Inoue…

Index: Organic Process Research and Development, , vol. 10, # 5 p. 905 - 913

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Citation Number: 44

Abstract

... Organic Process Research & ... Synthesis of (S)-3-(N-Methylamino)-1-(2-thienyl)propan-1-ol: Revisiting Eli Lilly's Resolution−Racemization−Recycle Synthesis of Duloxetine for Its Robust Processes. ... 2-2-3 Murotani, Nishi-ku, Kobe, 651-2241 Japan. Org. Process Res. Dev. ...