Simple method for the synthesis of 3-(pyrrolidin-1-yl) piperidine

RV Smaliy, AA Chaykovskaya, AA Yurchenko…

Index: Smaliy; Chaykovskaya; Yurchenko; Lakhtadyr; Shtil; Kostuk Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 9 p. 1178 - 1179

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Abstract

3-(Pyrrolidin-1-yl) piperidine (1) is a conformationally rigid diamine having major importance in medicinal chemistry [1-4]. The currently known method for the synthesis of this compound is of little use for the production of large quantities, being a complex, six-stage modification ...