Tetrahedron letters

“Armed-disarmed” glycosidation strategy based on glycosyl donors and acceptors carrying phosphoroamidate as a leaving group: A convergent synthesis of …

S Hashimoto, H Sakamoto, T Honda, H Abe…

Index: Hashimoto, Shun-Ichi; Sakamoto, Hiroki; Honda, Takeshi; Abe, Hiroshi; Nakamura, Sei-Ichi; Ikegami, Shiro Tetrahedron Letters, 1997 , vol. 38, # 52 p. 8969 - 8972

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Citation Number: 78

Abstract

A stereocontrolled synthesis of globotriaosylceramide with three different glycosidic linkages has been accomplished by linear and convergent routes exploiting “armed-disarmed” glycosidation methodology based on glycosyl donors and acceptors carrying tetramethylphosphoroamidate as a leaving group. In particular, the convergent strategy featuring a coupling of a galactosyl-(1→ 4)-galactosyl donor with a glucosylceramide ...