Journal of heterocyclic chemistry

Derivatives of 2??oxo??3 (2H)??benzothiazolineacetonitrile and related compounds. II. Synthesis of 2??oxo??alkyl esters of 3 (2H)??benzothiazolineacetimidic acids and …

JJ D'Amico, FG Bollinger

Index: D'Amico, John J.; Bollinger, Frederic G. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1487 - 1496

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Citation Number: 5

Abstract

Abstract The reaction of the appropriate 2-benzothiazolinone or 2-benzoxazolinone under basic conditions with (1) 2-chloropropionitrile,(2) acrylonitrile,(3) 4-chlorobutyronitrile or (4) chloroacetonitrile afforded the nitriles 1–8. The reaction of various nitriles with alcoholic- hydrogen chloride solutions at low temperatures afforded the hydrogen chloride salts of the imino-ester which upon neutralization with potassium carbonate yielded the titled ...