Tetrahedron letters

Indium-mediated radical cyclization of iodoalkenes and iodoalkynes with and without allylic and propargylic leaving groups

…, S Obika, N Nishimori, M Yamauchi, Y Takemoto

Index: Yanada, Reiko; Obika, Shingo; Nishimori, Nobuaki; Yamauchi, Masashige; Takemoto, Yoshiji Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2331 - 2334

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Citation Number: 25

Abstract

Upon treatment with In and I2, mono-substituted alkenes having an iodine substituent at the δ-position of the tether gave the corresponding iodinated cyclic compounds, whereas di-and tri-substituted alkenes gave the corresponding hydroxylated cyclic compounds. Alkenes bearing leaving groups at the allylic position were transformed only to the corresponding vinyl substituted cyclic compounds. On the other hand, alkynes bearing good leaving ...