Human immunodeficiency virus type 1 (HIV-1) is the major pathogen of the infection of acquired immunodeficiency syndrome (AIDS) [1]. In the past two and half decades, various compounds have been developed as medicinal candidates for the treatment of HIV infections aiming at one or several steps of the HIV-1 life cycle [2,3,4,5] such as absorption, entry, fusion, un-coating, reverse transcription, integration, transcription and maturation. Owing to the facts that HIV ...