Re-engineering of the Duocarmycin structural architecture enables bioprecursor development targeting CYP1A1 and CYP2W1 for biological activity

HM Sheldrake, S Travica, I Johansson…

Index: Journal of Medicinal Chemistry, , vol. 56, # 15 p. 6273 - 6277

Full Text: HTML

Citation Number: 18

Abstract

... Journal of Medicinal Chemistry. ... Chem. , 2013, 56 (15), pp 6273–6277. DOI: 10.1021/jm4000209. Publication Date (Web): July 11, 2013. Copyright © 2013 American Chemical Society. *Phone: +44 (0)1274 236482. Fax: +44 (0)1274 233234. ...