Tetrahedron Letters

A facile synthesis of muscimol

BE McCarry, M Savard

Index: McCarry; Savard Tetrahedron Letters, 1981 , vol. 22, # 51 p. 5153 - 5156

Full Text: HTML

Citation Number: 8

Abstract

... Abstract. The psychoactive isoxazole muscimol 10 has been synthesized in three steps from propargyl chloride. Download full text in PDF. Tetrahedron Lettess,Vo1.22,No.51,pp 5153-5156,1981 0040-4039/81/515153-04$02.00/0 Printed in Great Britain 981 Pergamon Press

~65%

~82%

Generation and reactions of the dianion of 3-hydroxy-5-methy...

[Oster, Timothy A.; Harris, Thomas M. Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4307 - 4311]

A convenient synthesis of muscimol by a 1, 3-dipolar cycload...

[Chiarino, D.; Napoletano, M.; Sala, A. Tetrahedron Letters, 1986 , vol. 27, # 27 p. 3181 - 3182]

A shorter synthesis of muscimol

[Welch, W. M. Synthetic Communications, 1982 , vol. 12, # 14 p. 1089 - 1091]

Synthesis and pharmacology of 3-isoxazolol amino acids as se...

[Nakamura, Norio; Tajima, Yawara; Sakai, Kiyoshi Heterocycles, 1982 , vol. 17, p. 235 - 245]