Tetrahedron letters

Synthesis of thio-and selenoglycosides by cleavage of dichalconides in the presence of zinc/zinc chloride and reaction with glycosyl bromides

C Mukherjee, P Tiwari, AK Misra

Index: Mukherjee, Chinmoy; Tiwari, Pallavi; Misra, Anup Kumar Tetrahedron Letters, 2006 , vol. 47, # 4 p. 441 - 445

Full Text: HTML

Citation Number: 44

Abstract

A convenient odorless methodology has been devised for the preparation of 1, 2-trans-thio- and selenoglycosides through zinc-mediated cleavage of disulfides and diselenides and reaction of the thiolate and selenides formed in situ with glycosyl bromides. The yields were excellent in all cases.