The class of 2-and 4-aminopyridinecarboxylic acid derivatives contains compounds possessing anxiolytic, anticonvulsant, and antiamnesic activity [1–3]. This study was devoted to the search for new effective anxiolytics among 4-amino-2, 6-dimethylnicotinic acid esters and amides. In the first step, 4-chloro-2, 6-dimethylnicotinic acid ethylate (I)[4] reacted with the corresponding amines to yield 4-amino-2, 6-dimethylnicotinic acid ethyl esters (IIa–IIf, ...
