Efficient Synthesis of 3-Arylphthalides using Palladium-Catalyzed Arylation of Aldehydes with Organoboronic Acids

M Kuriyama, N Ishiyama, R Shimazawa…

Index: Kuriyama, Masami; Ishiyama, Natsuki; Shimazawa, Rumiko; Shirai, Ryuichi; Onomura, Osamu Journal of Organic Chemistry, 2009 , vol. 74, # 23 p. 9210 - 9213

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Citation Number: 30

Abstract

The synthesis of 3-arylphthalides via palladium-catalyzed arylation of aldehydes with organoboronic acids was achieved using the thioether-imidazolinium carbene ligand in good to excellent yields and was carried out using 1.0 mol% of the catalyst with high substrate tolerance.