Improved fischer indole reaction for the preparation of N, N-dimethyltryptamines: synthesis of L-695,894, a potent 5-HT1D receptor agonist

C Chen, CH Senanayake, TJ Bill…

Index: Journal of Organic Chemistry, , vol. 59, # 13 p. 3738 - 3741

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Citation Number: 143

Abstract

... Chem., Vol. ... Chracterization of hemiacetal 18: 'H NMR (DMSO-&) 6 1.90(m, 3H), 2.25(m, lH), 2.75 (s,3H), 2.92 (a, 3H), 3.43 (m, 2H), 5.11 (t, J = 6.8 Hz, lH), 7.45 (br a, 1H); 13C NMR (DMSOdd 6 17.1, 27.0, 41.7 ... The organic layer was dried (Na804) and concenbated under vacuum ...