Synthesis and antimonoamine oxidase activity of an indole analog of deprenyl

…, YI Smushkevich, NN Suvorov, LI Gridneva…

Index: Dolicheva, I. N.; Smushkevich, Yu. I.; Suvorov, N. N.; Gridneva, L. I.; Gorkin, V. Z.; et al. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 603 - 607 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1033 - 1037

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Abstract

It has been proposed that for selective inhibition of monoamine oxidase A and B activities, not only the alkylation of the flavin component of monoamine oxidase [7] but also the interaction of the inhibitor with the hydrophobic portion of the enzyme [2, 3]~ has major significance.