Journal of Molecular Catalysis A: Chemical

Synthesis and application of peripherally alkyl-functionalized dendritic pyrphos ligands: Homogeneous-supported catalysts for enantioselective hydrogenation

B Yi, HP He, QH Fan

Index: Yi, Bing; He, Hua-Ping; Fan, Qing-Hua Journal of Molecular Catalysis A: Chemical, 2010 , vol. 315, # 1 p. 82 - 85

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Citation Number: 8

Abstract

A new series of dendritic ligands with a chiral diphosphine located at the focal point have been synthesized through coupling of (R, R)-3, 4-bis (biphenylphosphino) pyrrolidine (pyrphos) with peripherally alkyl-functionalized benzoic acid dendrons. These ligands were employed in the Rh-catalyzed asymmetric hydrogenation of prochiral dehydroamino acids, exhibiting excellent catalytic activities and enantioselectivities. The second-generation ...