Reductive coupling of N-methoxycarbonyl lactams with benzophenone and 9-fluorenone by low-valent titanium

…, Y Takenaga, Y Ishikawa, Y Morikami, T Sakurai

Index: Kise, Naoki; Takenaga, Yosei; Ishikawa, Yohei; Morikami, Yoichi; Sakurai, Toshihiko Tetrahedron Letters, 2012 , vol. 53, # 15 p. 1940 - 1945

Full Text: HTML

Citation Number: 6

Abstract

The reductive coupling of N-methoxycarbonyl lactams with benzophenone by Zn-TiCl4 in THF gave cross-coupled products as cyclic α-diphenylidene-N-methoxycarbonylamines and ring-opening α, α-diphenyl-α-hydroxy-ω-(N-methoxycarbonyl) amino ketones selectively depending on the reduction conditions. The reductive coupling of N-methoxycarbonyl lactams with 9-fluorenone by Zn-TiCl4 gave cyclic α-(9H-fluoren-9-ylidene)-N- ...