Synthesis and Antimycobacterial Activity of Novel Thiadiazolylhydrazones of 1??Substituted Indole??3??carboxaldehydes

K Haj Mohammad Ebrahim Tehrani…

Index: Haj Mohammad Ebrahim Tehrani, Kamaleddin; Mashayekhi, Vida; Azerang, Parisa; Sardari, Soroush; Kobarfard, Farzad; Rostamizadeh, Kobra Chemical Biology and Drug Design, 2014 , vol. 83, # 2 p. 224 - 236

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Citation Number: 2

Abstract

A series of novel thiocarbohydrazones of substituted indoles and their corresponding thiadiazole derivatives were prepared, and their structures were confirmed by different analytical and spectroscopic methods. The derivatives were prepared by a sequential synthetic strategy including substitution at N-1 position of indole ring by various aliphatic and benzylic substituents, followed by condensation with thiocarbohydrazide, and finally ...